SecStrAnnotator:Introduction - Revision history

Midlik at 14:55, 9 April 2020

2020-04-09T14:55:47Z

← Older revision		Revision as of 14:55, 9 April 2020
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	But first we must me able to orient within the collected data. '''Secondary structure elements (SSEs)''', mainly '''helices''' and '''β-strands''', are inherent parts of protein structures and their arrangement is characteristic for each protein family – they are something like bones in an animal body. Therefore, identification and annotation (naming) of the SSEs can facilitate orientation in the vast number of structures in each protein family. Annotated SSEs can be used as a reference to describe the position of the key regions (active sites, channel etc.), as tools to characterize the general anatomy of a family or to compare its members, and their relation to the protein function can be studied.		But first we must me able to orient within the collected data. '''Secondary structure elements (SSEs)''', mainly '''helices''' and '''β-strands''', are inherent parts of protein structures and their arrangement is characteristic for each protein family – they are something like bones in an animal body. Therefore, identification and annotation (naming) of the SSEs can facilitate orientation in the vast number of structures in each protein family. Annotated SSEs can be used as a reference to describe the position of the key regions (active sites, channel etc.), as tools to characterize the general anatomy of a family or to compare its members, and their relation to the protein function can be studied.

	'''SecStrAnnotator''' is tool which can be used for automated annotation of SSEs within protein families. It means that it assigns names to the SSEs in such way that the ~~corresponding~~ SSEs in each member of the family have the same name.		'''SecStrAnnotator''' is a tool which can be used for automated annotation of SSEs within protein families. It means that it assigns names to the SSEs in such way that the equivalent SSEs in each member of the family have the same name.

Midlik at 18:28, 7 March 2019

2019-03-07T18:28:43Z

← Older revision		Revision as of 18:28, 7 March 2019
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	'''SecStrAnnotator''' is tool which can be used for automated annotation of SSEs within protein families. It means that it assigns names to the SSEs in such way that the corresponding SSEs in each member of the family have the same name.		'''SecStrAnnotator''' is tool which can be used for automated annotation of SSEs within protein families. It means that it assigns names to the SSEs in such way that the corresponding SSEs in each member of the family have the same name.


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			[[SecStrAnnotator:UserManual \| Back to the main page]]

Midlik at 11:57, 1 May 2018

2018-05-01T11:57:40Z

← Older revision		Revision as of 11:57, 1 May 2018
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	A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays. Similar structures can be grouped together in so called '''protein families'''. As more and more structures are being collected in each family, the protein families have become very rich datasets. Based on these data, we can reach key research results – from understanding biomacromolecular functions and mechanisms of their action to the classification of types of diseases or the rational development of novel drugs.		A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays. Similar structures can be grouped together in so called '''protein families'''. As more and more structures are being collected in each family, the protein families have become very rich datasets. Based on these data, we can reach key research results – from understanding biomacromolecular functions and mechanisms of their action to the classification of types of diseases or the rational development of novel drugs.

			But first we must me able to orient within the collected data. '''Secondary structure elements (SSEs)''', mainly '''helices''' and '''β-strands''', are inherent parts of protein structures and their arrangement is characteristic for each protein family – they are something like bones in an animal body. Therefore, identification and annotation (naming) of the SSEs can facilitate orientation in the vast number of structures in each protein family. Annotated SSEs can be used as a reference to describe the position of the key regions (active sites, channel etc.), as tools to characterize the general anatomy of a family or to compare its members, and their relation to the protein function can be studied.

			'''SecStrAnnotator''' is tool which can be used for automated annotation of SSEs within protein families. It means that it assigns names to the SSEs in such way that the corresponding SSEs in each member of the family have the same name.

Midlik at 11:18, 1 May 2018

2018-05-01T11:18:44Z

← Older revision		Revision as of 11:18, 1 May 2018
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	A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays.		A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays. Similar structures can be grouped together in so called '''protein families'''. As more and more structures are being collected in each family, the protein families have become very rich datasets. Based on these data, we can reach key research results – from understanding biomacromolecular functions and mechanisms of their action to the classification of types of diseases or the rational development of novel drugs.

Midlik: Created page with "A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays."

2018-05-01T10:47:55Z

Created page with "A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays."

New page

A tremendous number of protein structures is available in the [https://www.ebi.ac.uk/pdbe/ Protein Data Bank (PDB)] nowadays.