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=1. Software requirements= '''CrocoBLAST''' runs on Windows and Linux. Mac OS users can use CrocoBLAST by creating a Linux virtual machine in their Mac computer. Instructions on how to run CrocoBLAST on Mac are found in chapter VI of this manual. CrocoBLAST is able to produce its output on 3 of the BLAST output formats. Once you download the "zip" with all necessary '''CrocoBLAST''' files, all you need to do is unzip it to the desired location. As CrocoBLAST works as a wrapper for BLAST, you will need to have BLAST available on your computer before you can run CrocoBLAST. If you don't already have BLAST, please [https://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE_TYPE=BlastDocs&DOC_TYPE=Download get the latest version from the NCBI website]. No further requirements exist for running the command line utility of '''CrocoBLAST''', or inspecting the results. In Windows, downloading files from the NCBI server requires PowerShell, which ships automatically with Windows 7 and newer, and can be installed on Windows XP and Vista. The graphical user interface requires Java 8, which is likely already installed on your computer. If not, please visit https://java.com/en/download/.
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