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==Hardware requirements== Because of the nature of the data being processed, it is better if your computer has at least 200 MB of RAM per core. Nonetheless, it is possible to run CrocoBLAST on big data files even if less memory is available, but you will need to specify this fact during [[CrocoBLAST:JobManagement#JobSubmission| job submission]]. Furthermore, if you need to analyze NGS data,the input and output files involved in such calculations can be quite large, and therefore you will need to have sufficient space on your hard disk. NCBI databases range from 10 MB to 500 GB (whole genomes). Depending on the type of sequencing experiment you ran, your input files may range from a few kB to 100 GB. If you don't specify any BLAST options, the size of the output file may be up to 1300 times the size of the input file. Nevertheless, in the typical use case, requesting relevant BLAST options (e.g., provide only the first 20 hits) will greatly reduce the size of the output file.
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